Senescence follows bionics doctor and ex-drug addict, Clarence, as he meets a new friend after the loss of an old one. With over a millennia’s experience in the stars, the Amalgamate, Rüdiger, helps Clarence understand the true wonder and fragility of humanity and mortality. The cyborg show’s Clarence that one is never too old for childish amazement and discovery, leaving the doctor to struggle with his own mortality and the decision to stay on a planet he only holds hatred towards or to leave and discover something new for himself.